Adore - Research Institute for Oncology and Neurology

In the Netherlands, one in two people will develop cancer, one in five will develop dementia (among women, this figure rises to one in three), and every day someone is diagnosed with multiple sclerosis (MS). These diseases have an enormous impact on patients and their loved ones and call for new ways of collaborating and conducting research. This is where ADORE (AmsterDam Oncology and Neuroscience Research) plays a unique role, a revolutionary initiative that brings together two fields of research – oncology and neurology – in a unique way.

At this largest onco-neurocampus in the world, more than 2,000 researchers are working together on innovative projects. In an inspiring new building, top researchers from home and abroad come together, with access to the most advanced equipment. Here, traditional boundaries are broken down and work is being done on disease-transcending solutions for conditions that affect millions of people.

Message in a Vesicle

This research focuses on gaining a better understanding of brain diseases such as Alzheimer's and brain tumours. Researchers are looking at extracellular vesicles – tiny “messages” that cells pass on to each other. When brain cells become diseased, their contents change. The technique developed by ADORE makes it possible to measure these changes in patients. This offers opportunities for scientists to recognise diseases earlier and develop new treatments for brain disorders.

SCAPE

The second study, SCAPE (Single-Cell Adore Proteomics Exploration), investigates how proteins in individual cells contribute to diseases such as cancer and dementia. This new technique makes it possible to measure all proteins in a single cell. By analysing the communication between individual cells, without the image being distorted by thousands of other cells, researchers can detect disease-causing proteins that reveal more about how diseases develop and worsen. With these insights, scientists can develop more targeted treatments that intervene precisely where needed, offering opportunities for better care in the future.

Op deze grootste onco-neurocampus ter wereld werken meer dan 2000 onderzoekers samen aan vernieuwende projecten. In een inspirerend nieuw gebouw komen toponderzoekers uit binnen- en buitenland samen, met toegang tot de meest geavanceerde apparatuur. Hier worden tradiotionele grenzen doorbroken en wordt gewerkt aan ziekte-overstijgende oplossingen voor aandoeningen die miljoenen mensen raken.